Further information on the vaccines and study groups can be found in the study information sheet (PIS). Please answer the questions below to register your interest and our study team will get in touch. Are you aged between 18 and 45? * Yes No Are you in good health? * Yes No Can you easily attend regular visits at the Churchill Hospital, Oxford? * Yes No Have you read the participant information sheet? * Yes No Are you registered with a GP practice in the UK? * Yes No Are you currently pregnant, breastfeeding or planning on becoming pregnant in the next 12 months? * Yes No Do you agree to not donate blood whilst in the trial (up to 2.5 years)? * Yes No Do you have any history of cancer (excluding basal cell carcinoma of the skin or cervical carcinoma in situ)? * Yes No Have you ever had malaria? * Yes No Have you ever had a malaria vaccine? * Yes No Have you ever had anaphylaxis after a vaccination? * Yes No Do you drink on average more than 25 units of alcohol a week? The NHS recommends the following calculator: https://alcoholchange.org.uk/alcohol-facts/interactive-tools/unit-calculator * Yes No Have you injected recreational drugs in the last 5 years? * Yes No Thank you for your interest in the trial. In order to help manage the risks of COVID-19 we are trying to minimise the time volunteers spend at our screening visits. To help with this, we would like to gather information about your medical history here. This will be used to help decide if you are eligible to take part in the study. Giving your consent means that you are happy for us to store and use your personal information for the purposes of this trial. Information will be stored in accordance with the UK GDPR and Data Protection Act. Further information can be found at: https://compliance.web.ox.ac.uk/individual-rights I agree for the Oxford Vaccine Group to record my personal information and information about my medical history. I agree to be contacted by the Oxford Vaccine Group for the purposes of this trial. * Yes No Thank you for your responses. You may be eligible to participate in this trial. Please proceed to the next section where we will ask for your consent to record more medical information. What is your title? E.g. Mrs, Miss, Ms, Mr, Dr, Prof * What is your full first name (as it appears on your passport/ birth certificate) * What is your last name? * What is your date of birth? * Day Day12345678910111213141516171819202122232425262728293031 Month MonthJanFebMarAprMayJunJulAugSepOctNovDec Year Year1979198019811982198319841985198619871988198919901991199219931994199519961997199819992000200120022003200420052006 What was your sex recorded at birth? * Male Female Is your current sex and/or gender the same as sex at birth? * Yes No If no, how would you describe your current gender? * Male/man Female/woman Non-binary Not listed If not listed, please describe * How will you mainly attend your clinic visits? * Solely reliant on public transport Car Motorbike Bicycle Walking What is your email address? * What is your phone number? * What is your address? * What is your postcode? * What are your GP practice details? * Do you have any medical conditions? * Yes No If yes, please list all here * Do you have any mental health conditions? * Yes No If yes, please list all here * Have you ever had any operations? * Yes No If yes, please list all here * Have you seen a doctor about anything else in the past 12 months? * Yes No If yes, please list all here * Are you currently taking any medication? * Yes No Please list here * It is very important that volunteers do not become pregnant during the trial because we don’t know how the vaccines could affect an unborn baby Have you ever been potentially able to become pregnant? * Yes No If yes, are you willing to agree to one of the following until 3 months after your final trial vaccination? Please note condoms alone are not considered effective enough as contraception during the trial. * I have had a total hysterectomy (surgical removal of the womb). I have had bilateral tubal occlusion (commonly referred to as “tube-tie” or “female sterilisation”) I am post-menopausal. I have not had any periods for at least 12 months and am not on any hormonal contraception. I have seen my GP and they have not found any other reason for my periods stopping. I completely avoid any sexual relationship in which I might become pregnant (for example, I only have female partners or I do not have sexual relationships at all). My partner has had male sterilisation (vasectomy) – and this is my only partner. I use oral, injected or implanted hormonal contraception e.g. “the pill”, “mini-pill”, “depot injection” or “implant”. I have an intrauterine device (IUD) or intrauterine system (IUS) (commonly referred to as having “a coil”). None of the above are applicable to me (and I will not be able to join the trial). Have you travelled abroad in the past 6 months * Yes No If yes, please list the countries you have visited * Are you planning to travel abroad in the next 2 years * Yes No If yes, please list the countries you plan to visit * Have you ever lived outside of the UK for more than 6 months? * Yes No If yes please list the countries you have lived in and the duration of time you lived there * Have you had a blood transfusion or received other blood products (such as immunoglobulins) in the past 3 months? * Yes No If yes, please detail * Have you had any vaccinations in the past 30 days? * Yes No If yes, please detail * Do you have any vaccinations planned in the next year? * Yes No If yes, please detail * Are you currently taking part in any other research studies? * Yes No If yes, please detail * Have you ever had any vaccinations as part of a clinical trial? * Yes No If yes, please detail * Do you have any problems with your immune system? This includes having had your spleen removed, a tendency to infections or taking any medication that suppresses your immune system. * Yes No If yes, please detail * Have you ever been told you have hepatitis B, hepatitis C or HIV infection? * Yes No If yes, please detail (include any treatment received) * Do you have any allergies? (All allergies including food, medication and insect bites/stings) * Yes No If yes, please detail * Thank you for your interest. Unfortunately, you are not eligible to join this trial. Your data has not been stored. If you are interested in hearing more about our other studies, you can sign up to our newsletter here http://newsletter.ovg.ox.ac.uk/OVG/lists/?p=subscribe&id=1 Thank you, but unfortunately you need to be within easy traveling distance of a study site. Unfortunately, we can’t consider you for this trial until you have read the participant information leaflet provided at: PIS Please read the leaflet and then resume this questionnaire if you are still interested in participating in the trial Math question * 3 + 0 = Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.