Understanding RSV: Severe disease and the long term consequences

Oxford Vaccine Group are currently inviting children under 12 months of age to take part in a study which will help us learn more about the virus that most commonly causes coughs, colds and chest infections in young children and can sometimes cause children to be so unwell they have to be admitted to hospital.

More than half of children will be infected with the virus, called Respiratory Syncytial Virus (RSV) in their first year of life, mostly during the winter.

We hope to understand why some children will have severe RSV disease, identify a measure that indicates who is likely to get severe RSV disease and which children will go on to develop long term problems, such as wheezing.

Children with symptoms of a respiratory illness such as coughs, runny or blocked noses or sneezes may be able to take part.  By taking a swab from your child’s nose we can test to see if the illness is caused by the RSV virus.  If it is, your child would be able to take part in the study. 

In the study we would take swabs from your child’s nose, take a small amount of blood and collect samples of urine and stool from the nappy.  We would do this once when your child is first unwell and then again around 7 weeks later. We would visit you at home or wherever is most convenient for you.

We would also need you to complete a daily diary for 14 days and complete a questionnaire every year for up to three years.

If you are interested in taking part in this study please read the study information booklet.

If you would like to discuss the study or have any questions please contact the study team on;

01865 611400 or email resceu@ovg.ox.ac.uk .

If you would like to register to take part, please fill in the questions below.  It is important for you to know that all answers will be kept confidentially by the study team.

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