Burden of RSV Disease

Some facts about RSV disease (respiratory syncytial virus):

RSV is a virus;

  • it causes coughs, colds and chest infections
  • is responsible for around 1 in 6 hospital admissions for infants  in the UK
  • The second largest worldwide cause of deaths in children between one month and 1 year of age, most are in Asia and Africa

What do we want to do?

We would like to identify 2000 babies from birth and follow them up to see if any become unwell with RSV disease

Understanding Pneumococcal Carriage and Disease 2017/2018

The Oxford Vaccine Group is currently inviting healthy children aged 13 – 48 months to take part in a swabbing study looking at how much pneumococcal bacteria is carried in the nose.

Streptococcus pneumoniae is a type of bacteria that is carried (lives) in the nose of most individuals at some time in their lives and can sometimes go on to cause severe infections such as meningitis and pneumonia. There are over 100 types of pneumococcus and children in the UK have been routinely immunised against pneumococcal disease since 2006.

ImmunoglobuliN in the Treatment of Encephalitis

The IgNiTE Study

A study testing a new treatment for children with encephalitis.

The Department of Paediatrics at the University of Oxford, in collaboration with NHS Trusts across the United Kingdom, is currently running a study for hospitalised children with encephalitis. The study will assess whether a treatment called intravenous immunoglobulin (IVIg, sometimes referred to as antibody treatment) has any benefit for these children when given early during the hospital admission.

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